STANDARDISASI EKSTRAK ETANOL BIJI BAGORE (Caesalpinia crista L.).
Abstract
Bagore plant (Caesalpinia crista L.) belongs to the tribe Leguminosae and grows wild on the coast. Standardization is important to guarantee potency uniformity benefits by ensuring the concentration of active ingredients through qualitative analysis of secondary metabolites, ensuring the safety and stability aspects of extracts and increasing the economic value of extracts by various analyses such as specific and non-specific parameters. This study aims to standardization bagore seed extract (Caesalpinia crista L.) and determine the value of specific and non-specific parameters of. Samples were obtained from Binuang District, Polewali Mandar Regency, West Sulawesi Province, macerated with 96% ethanol then standardized with specific and non-specific parameters. The results of the study obtained specific parameter values as follows; organoleptic tests obtained extracts in the form of viscous, light brown in color, characteristic smell and very bitter taste; The content of soluble compounds in water is 14.361%; the content of soluble compounds in ethanol is 15.708%; positively contains flavanoid compounds, alkaloids and saponins; and the value of non-specific parameters as follows: drying shrinkage which is 0.439%; specific weight of 0.859 grams; moisture content of 2.589%; total ash content of 4.216%, insoluble ash content of acid which is 0.630%; The mold number is < 1.0 x 101 colonies/ml and the yeast is < 1.0 101 colonies/ml; lead metal contamination (Pb) is 0.003 g / g and cadmium (Cd) is 0.01 g / g. Research shows bagore seed extract (Caesalpinia crista L.) provides results according to the general standard parameters of medicinal plant extracts.
Keyword : Bagore seed, Caesalpinia crista L., standardization, spesific parameters, non-spesific parameters.
References
2. Sodhi JK, Shrivastava B, Lamba HS, Kaur A, Sharma PK. Caesalpinia crista seeds-in vivo screening of hepatoprotective efficacy against CCL4 induced hepatotoxicity. Int J Health Sci (Qassim). 2022;6(March):10330–40.
3. Ramadani FR, Saisa S, Ceriana R, Andayani T. Pemanfaatan Kulit Buah Naga Merah (Hylocereus polyrhizus) sebagai Pewarna Alami Kosmetik Pemerah Pipi (Blush On). J Healthc Technol Med. 2018;4(2):165.
4. Departemen Kesehatan RI. Parameter Standar Umum Ekstrak Tumbuhan Obat. 2000.
5. Handayani V, Rahman S, Amaliah ANA. UJI TOKSISITAS EKSTRAK ETANOL BATANG KAYU WOLE WOE TERHADAP LARVA Artemia salina Leach MENGGUNAKAN METODE Brine Shrimp Lethality Test (BSLT). As-Syifaa J Farm. 2022;14(2):131–8.
6. Mustapa MA, Abdulkadir WS, Halid IF. STANDARISASI PARAMETER SPESIFIK EKSTRAK METANOL BIJI KEBIUL (Caesalpinia Bonduc L.) SEBAGAI BAHAN BAKU OBAT HERBAL TERSTANDAR. J Syifa Sci Clin Res. 2020;2(1):49–58.
7. Yanty YN, Sopianti DS, Veronica C. Fraksinasi dan Skrining Fraksi Biji Kebiul (Caesalpinia bonduc (L) Roxb) dengan Metode KLT (Kromatografi Lapis Tipis). Borneo J Phamascientech. 2019;3(1):56–64.
8. Handayani V, Syarif RA, Najib A, Ahmad AR, Mahmud A, St NJ. Standardization and bacteria inhibitory test of purified extract of mahogany (Swietenia mahagoni (L.) Jacq) seeds and leaves. Int J Res Pharm Sci. 2019;10(3):2132–8.
9. Kusuma AE, Aprileili DA. Pengaruh Jumlah Pelarut Terhadap Rendemen Ekstrak Daun Katuk ( Sauropus androgynus L. Merr). J Farm Sains dan Obat Tradis. 2022;125–35.
10. Saifudin A, Rahayu V, Teruna HY. Standardisasi Bahan Obat Alam. 2011.
11. Putri DM, Lubis SS. Skrining Fitokimia. J Chem Inf Model. 2020;53(9):1689–99.
12. Illing, Ilmiati; Safitri WE. UJI FITOKIMIA EKSTRAK BUAH DENGEN Ilmiati Illing * , Wulan Safitri dan Erfiana. 2017;66–84.
13. Syarif RA, Handayani V, Angraeni A. Standarisasi Ekstrak Etanol Buah Bintaro (Cerbera odollam Gaertn.) Sebagai Obat Tradisional. J Fitofarmaka Indones. 2022;9(2):7–13.
14. Utami YP, Umar AH, Syahruni R, Kadullah I. Standardisasi Simplisia dan Ekstrak Etanol Daun Leilem ( Clerodendrum. J Pharm Med Sci. 2017;2(1):32–9.
15. BPOM. Persyaratan Mutu Obat Tradisional. Badan Pengawas Obat dan Makanan. 2014;1–25.